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Search Results for " leukotriene biosynthesis "

16

Compounds

Cat No. Product Name Synonyms Targets
T6893 MK-886 MK886,L 663536 Apoptosis , Leukotriene Receptor , COX , PPAR , FLAP
MK-886 (L 663536) is an inhibitor of leukotriene biosynthesis, inhibiting 5-lipoxygenase-activating protein (FLAP). It is also a moderately potent PPARα antagonist.
T7786 Tryptanthrin DNA gyrase
Tryptanthrin is a natural DNA gyrase inhibitor.
T24327 L 674573 L 674,573,L674,573,L-674,573,L674573,L-674573 Leukotriene Receptor
L 674573 is an inhibitor of leukotriene biosynthesis.
T77638 BIRM 271 Phospholipase , LTR
BIRM 271 is a novel arachidonic acid release inhibitor that blocks leukotriene B4 and platelet-activating factor biosynthesis in human neutrophils. BIRM 271 and BIRM 270 are enantiomers that inhibit the production of leu...
T16087 Quiflapon MK-591 Apoptosis , FLAP
Quiflapon (MK-591) causes cell apoptosis. Quiflapon is a selective and specific 5-lipoxygenase-activating protein (FLAP) inhibitor (IC50: 1.6 nM in a FLAP binding assay) and is also an effective and orally active Leukotr...
T24322 L 669083 L669,083,L-669,083,L 669,083,L-669083,L669083
L 669083 is two classes of potent leukotriene biosynthesis inhibitors photoaffinity analogue.
T24340 L 691678 L-691678,L691678
L 691678 is a potent leukotriene biosynthesis inhibitor.
T24337 L 689037 L-689037,L689037,L689,037,L 689,037,L-689,037
L 689037 is an inhibitor of leukotriene biosynthesis.
T71309 MK-886 sodium salt
MK-886 sodium salt inhibits leukotriene biosynthesis in leukocytes.
T68314 DG-051
DG-051 is a novel leukotriene A4 (LTA4H) hydrolase inhibitor of leukotriene B4 biosynthesis.
T69385 Baicalein monohydrate
Baicalein monohydrate is an inhibitor of 12-lipoxygenase, leukotriene biosynthesis and release of lysosomal enzymes. It also inhibits cellular Ca2+ uptake and mobilization and adjuvant-induced arthritis.
T73793 20-Carboxy-Leukotriene B4
20-Carboxy-Leukotriene B4 (20-COOH LTB4), a metabolite of Leukotriene B4 (LTB4), exhibits high affinity binding to the BLT1 receptor. It notably inhibits LTB4-mediated neutrophil responses, including migration, degranula...
TN6057 1-Methyl-2-[(Z)-6-undecenyl]-4(1H)-quinolone (Z)-1-Methyl-2-(undec-6-enyl)quinolin-4(1H)-one
(Z)-1-Methyl-2-(undec-6-enyl)quinolin-4(1H)-one shows strong inhibitory activity on leukotriene biosynthesis in human polymorphonuclear granulocytes, and it is very effective against mycobacteria.
TN2552 1-Methyl-2-nonylquinolin-4(1H)-one Others
1-Methyl-2-nonylquinolin-4(1H)-one has anti-inflammatory activity, it exhibits inhibitory activity on leukotriene biosynthesis in a bioassay using human polymorphonuclear granulocytes, with IC50 values of 12.1 microM.
TN5070 Stilbostemin B Others
Stilbostemin A, stilbostemin B , stilbostemin D , stilbostemin F , and stilbostemin G show structure-dependent inhibition of leukotriene biosynthesis with IC(50) values ranging from 3.7 to >50 microM.
T27026 CJ-13,610 CJ 13610,CJ-13610 Lipoxygenase
CJ-13,610 is an orally active and nonredox-type inhibitor of 5-lipoxygenase (5-LOX). CJ-13,610 inhibits the biosynthesis of leukotriene B4 and regulates the expression of IL-6 mRNA in macrophages.
TargetMol